The endocannabinoid system is modulated by diet, sleep, exercise, stress, and a multitude of other factors, including exposure to CBD. Modulating the activity of this system may offer tremendous therapeutic promise for a diverse scope of diseases, ranging from mental health disorders, neurological and movement disorders, pain, autoimmune disease, spinal cord injury, cancer, cardiometabolic disease, stroke, TBI, osteoporosis, and others.
Corroon, J., Felice, J.F. (2019). The endocannabinoid system and its modulation by cannabidiol (CBD). Alternative Therapies in Health And Medicine, 25, 6-14, Supplement: 2.
The endocannabinoid system is modulated by diet, sleep, exercise, stress, and a multitude of other factors, including exposure to CBD. Modulating the activity of this system may offer tremendous therapeutic promise for a diverse scope of diseases, ranging from mental health disorders, neurological and movement disorders, pain, autoimmune disease, spinal cord injury, cancer, cardiometabolic disease, stroke, TBI, osteoporosis, and others.
Corroon, J., Felice, J.F. (2019). The endocannabinoid system and its modulation by cannabidiol (CBD). Alternative Therapies in Health And Medicine, 25, 6-14, Supplement: 2.
Clinical and preclinical evidence suggesting CBD and other cannabinoids have therapeutic effects in Parkinson's disease and L-DOPA-induced dyskinesia.
Ferreira, N.C., dos-Santos-Pereira, M., Guimaraes, F.S., Del Bel, E. (2020). Cannabidiol and cannabinoid compounds as potential strategies for treating Parkinson's disease and L-DOPA-Induced dyskinesia. Neurotoxicity Research, 37 (1), 12-29. DOI: 10.1007/s12640-019-00109-8.
Combining photodynamic therapy with CBD will allow a substantial advance in the treatment of breast cancer and other types of cancers.
FMokoena, D.R., George, B.P., Abrahamse, H. (2019). Enhancing breast cancer treatment using a combination of cannabidiol and gold nanoparticles for photodynamic therapy. International Journal of Molecular Sciences, 20 (19), Article Number: 4771. DOI: 10.3390/ijms20194771 Published: OCT 2019.
We report here a patient with adenocarcinoma of the lung who, after declining chemotherapy and radiotherapy, presented with tumour response following self-administration of CBD. Prior work has shown that CBD may have anti-neoplastic properties and enhance the immune response to cancer. CBD might have led to a striking response in a patient with lung cancer.
Sulé-Suso, J., Watson, N.A., van Pittius, D.G., Jegannathen, A. (2019). Striking lung cancer response to selfadministration of cannabidiol: A case report and literature review. SAGE Open Medical Case Reports, Volume 7: 1–4.
Recent studies have confirmed the ability of CBD to alter important aspects of aversive memories in humans and promote significant improvements in the symptomatology of Post-traumatic stress disorder.
Bitencourt, R.M., Takahashi, R.N. (2018). Cannabidiol as a therapeutic alternative for post-traumatic stress disorder: From bench research to confirmation in human trials. Frontiers in Neuroscience, 12, Article Number: 502. DOI: 10.3389/fnins.2018.00502.
CBD emerges as a promising compound to treat and/or prevent movement disorders.
Peres, F.F., Lima, A.C., Hallak, J.E.C., Crippa, J.A., Silva, R.H., Abilio, V.C. (2018). Cannabidiol as a promising strategy to treat and prevent movement disorders? Frontiers in Pharmacology, 9, Article Number: 482. DOI: 10.3389/fphar.2018.00482.
CBD improves cognition in multiple preclinical models of cognitive impairment, including models of neuropsychiatric (schizophrenia), neurodegenerative (Alzheimer's disease), neuro-inflammatory (meningitis, sepsis and cerebral malaria) and neurological disorders (hepatic encephalopathy and brain ischemia).
Osborne, A.L., Solowij, N., Weston-Green, K. (2017).A systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia. Neuroscience and Biobehavioral Reviews, 72, 310-324. DOI: 10.1016/j.neubiorev.2016.11.012.
CBD seems to be a promising drug for the treatment of Panic disorder.
Soares, V.P., Campos, A.C. (2017). Evidences for the anti-panic actions of cannabidiol. Current Neuropharmacology, 15 (2), 291-299. DOI: 10.2174/1570159X14666160509123955.
